Impact of vitamin D status on risk of cardiovascular disease.

Impact of vitamin D status on risk of cardiovascular disease in healthy adults.

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000584235

Enrollment

Registered

2009-07-14

Start date

2009-09-03

Completion date

2013-10-24

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study aims to determine whether vitamin D deficiency is associated with increased cardiovascular risk and whether that risk is reversed by vitamin D replacement.

Interventions

Arterial stiffness and autonomic nervous system activity will be correlated with vitamin D status in a cross-sectional study. Subjects with vitamin D deficiency (25-hydroxy vitamin D < 50 nmol/L) will be restudied 4-6 weeks after replenishment of vitamin D stores (100000 IU vitamin D orally in two doses two weeks apart).

Study design

Allocation

Non-randomised trial

Primary purpose

Prevention

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy adults

Exclusion criteria

Treatment with 25-hydroxy vitamin D or 1,25-dihydroxy vitamin D Beta-blocker medication Diabetes mellitus Atrial fibrillation

Outcome results