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A comparison of flow reserve in skeletonized versus pedicled internal thoracic arteries during coronary artery bypass surgery?

A comparison of flow reserve in skeletonized versus pedicled internal thoracic arteries during coronary artery bypass surgery?

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000579291
Enrollment
80
Registered
2009-07-14
Start date
2009-08-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this project is to determine the best way to harvest an artery that is commonly used in cardiac surgery from behind the chest bone to allow best possible result.

Interventions

Patients having bilateral internal thoracic artery harvest for coronary bypass will be randomized to having one side dissected pedicled (artery and veins) or skeletonized (artery only) to determine if a method provides superior flow. Both arms of the study require diathermy dissection of the mammary artery of the chest wall and clipping of the branches of the artery. The two techniques differ as the pedicled approach involves clipping of the branches of both the mammary veins and artery and di

Patients having bilateral internal thoracic artery harvest for coronary bypass will be randomized to having one side dissected pedicled (artery and veins) or skeletonized (artery only) to determine if a method provides superior flow. Both arms of the study require diathermy dissection of the mammary artery of the chest wall and clipping of the branches of the artery. The two techniques differ as the pedicled approach involves clipping of the branches of both the mammary veins and artery and dissecting the mammary artery and veins en bloc from the chet wall while the skeletonized approach involves only clipping and dissection of branches of the mammary artery only and leaving the mammary veins in situ. Both techniques take approximately 30-40 minutes and both techniques are currently in widespread use.

Sponsors

Mr Phillip Hayward
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

Patients undergoing cardiac surgery who require use of bilateral internal thoracic arteries for coronary surgery.

Exclusion criteria

Emergency case Haemodynamically unstable patient

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026