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Effect of timing of morphine administration during propofol-remifentanil anesthesia on post operative analgesic requirement

Early versus late administration of morphine during propofol-remifentanil anesthesia to compare 24-hour post operative analgesic requirement in patients undergoing an open nephrolithotomy operation

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000570280
Enrollment
60
Registered
2009-07-13
Start date
2007-03-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Earlier use of long acting opioids like morphine during anesthesia to decrease total needed dose of analgesics after operation

Interventions

intravenous infusion of 0.1 mg/kg morphine over 2 minutes immediately after induction of anesthesia

Sponsors

Shiraz University of Medical Sciences
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

open nephrolithotomy operation

Exclusion criteria

Drug abuse

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026