Does nicotine improve selective attention more than placebo in healthy volunteers and what does this tell us about mechanisms of attention?

Does nicotine improve selective attention more than placebo in healthy volunteers?

Status

Not yet recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000511235

Enrollment

Registered

2009-06-29

Start date

2009-06-29

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Selective attention is a cognitive skill that allows us to interpret and act in our environment. Although this skill is important, little is understoond about the neurochemical processes that are important to attention. This study will allow us to assess the importance of different brain chemicals in contributing to selective attention function.

Interventions

Single application of nicotine patch (7mg) for 2 hours Please note: minimum washout period between conditions is 1 week

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Educational / counselling / training

Masking

Blinded (masking used)

Eligibility

Sex/Gender

Male

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy volunteers History of non-dependent nicotine exposure (e.g. casual smoker)

Exclusion criteria

Current smokers History of nicotine dependence Current or history of major psychiatric or neurological illness Current or history of substance dependence

Outcome results