Ethanol lock therapy for the prevention of tunnelled intravenous catheter-associated bacteraemias in patients with chronic renal failure undergoing haemodialysis via a central venous catheter insitu

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000493246

Acronym

Ethanol Trial

Enrollment

112

Registered

2009-06-22

Start date

2007-09-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The study is to lock a small amount of Ethanol in the center of the line for 48 hours each week in patients who have a tunnelled line, to prevent the development of catheter-associated bacteraemia in haemodialysis patients.

Interventions

3 mL intravenous 70% ethanol is instilled into each lumen of the tunnelled intravenous catheter as a lock, at the end of the haemodialysis treatment, once weekly. The ethanol is withdrawn before the next dialysis session, 48 hours later. The patient remains on the study until the catheter is removed.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Healthy volunteers

Inclusion criteria

Tunnelled central venous catheter in situ. Undergoing haemodialysis for chronic renal failure via the catheter. Agree to inclusion in the study.

Exclusion criteria

Evidence of current central venous catheter infection. Pregnant or breast feeding females. Religious objection to ethanol lock therapy

Outcome results