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Clinical Pathways for Acute Coronary Syndromes in China - phase 2: implementation and evaluation

In patients with acute coronary syndromes admitted to urban hospitals in China, are clinical pathways effective for improving the quality of care.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000491268
Acronym
CPACS-2
Enrollment
15000
Registered
2009-06-19
Start date
2007-10-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Coronary heart disease is now a leading cause of disease in China. The strategies for managing acute coronary syndromes (ACS) are well-recognised, however, anecdotal reports suggest that many patients do not receive recommended therapies. This study aims to develop, implement and evaluate quality improvement initiatives (using clinical pathways) throughout selected hospitals in China, to increase the use of recommended treatments and reduce the use of expensive and unnecessary investigations and treatment. Over the long term, this could lead to substantial reductions in the rates of disability and death due to ACS.

Interventions

Clinical pathways in this study are standardized algorithms for the treatment of acute coronary syndromes that aim to optimize and streamline patient care. They are established according to American Heart Association (AHA) and American College of Cardiology (ACC) guidelines to promote the use of evidence-based treatments for high risk patients and ultimately, improve clinical outcomes. The clinical pathways are designed to accompany the patient’s medical record and available in printed copy. In

Clinical pathways in this study are standardized algorithms for the treatment of acute coronary syndromes that aim to optimize and streamline patient care. They are established according to American Heart Association (AHA) and American College of Cardiology (ACC) guidelines to promote the use of evidence-based treatments for high risk patients and ultimately, improve clinical outcomes. The clinical pathways are designed to accompany the patient’s medical record and available in printed copy. In this study after baseline data collection, the printed clinical pathways as a reminder of guideline adherence will be added in front of patient’s medical record in relevant departments in the participating hospitals. The clinical pathways will be used for at least 24 month in participating hospitals. Its impact will be evaluated periodically (every 6 months) by comparing a series of key performance indicators, e.g. average door-to needle time and average door-to-balloon time for patients with ST elevated myocardial infarction.

Sponsors

Sanofi-Aventis (China)
Lead SponsorCommercial sector/Industry

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
17 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Hospitals routinely admitting patients with acute coronary syndromes are included in the study; patients over 17 years old and being hospitalised due to acute coronary syndromes are included in the study.

Exclusion criteria

Hospitals currently admitting fewer than 100 patients with suspected acute coronary syndromes per year will be excluded from the study.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 10, 2026