A randomized, placebo controlled trial of milk products for prevention of gout flares

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000479202

Enrollment

120

Registered

2009-06-17

Start date

2009-07-20

Completion date

2010-06-30

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is three-month study of milk products for prevention of gout attacks. Patients with recurrent gout attacks will be randomized to three separate milk powder arms; each product will be administered daily as a 250ml milk drink. The three groups will be a control milk product, a standard skim milk powder, and a skim milk powder enriched with anti-inflammatory factors. We will analyse whether any of the products tested reduces the frequency of gout attacks.

Interventions

Daily administration of one of three milk products (two intervention milk products plus one control milk product) for three months. The two intervention products are standard skim milk, and skim milk enriched with milk-derived anti-inflammatory products (Glycomacropeptide [GMP] and G600). Each product will be taken daily as a 250ml drink.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

1. Diagnosis of gout (based on American College of Rheumatology [ACR]criteria) 2. At least two gout flares in the last four months 3. Able to provide written informed consent 4. Age 18 years and above

Exclusion criteria

1. Lactose intolerance 2. Severe renal impairment (glomerular filtration rate [GFR]<30)

Outcome results