None listed
Conditions
Brief summary
The main purpose of the trial is to verify the efficacy of cetylpyridinium chloride mouthwashes in the treatment of denture stomatitis utilizing as outcome measures clinical and micological parameters, i.e., extent and intensity of mucosal erythema and colony forming units of Candida species.
Interventions
Once stablished the diagnosis of denture stomatitis, patients will be randomly allocated to one of two experimental groups. All patients will receive hygiene instructions and asked to avoid nocturnal use of their prosthesis. An appropriate toothbrush will be provided and a proper hygiene technique will be demonstrated and practiced once at the start of trial and reinforced at each control appointment. Test group will be given cetylpyridinium chloride and directions to mouthwash 3 times daily, d
Once stablished the diagnosis of denture stomatitis, patients will be randomly allocated to one of two experimental groups. All patients will receive hygiene instructions and asked to avoid nocturnal use of their prosthesis. An appropriate toothbrush will be provided and a proper hygiene technique will be demonstrated and practiced once at the start of trial and reinforced at each control appointment. Test group will be given cetylpyridinium chloride and directions to mouthwash 3 times daily, during one minute, three weeks long. Control group will be followed with no other intervention but the hygiene instructions.
Sponsors
Sao Paulo University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No
Inclusion criteria
Removable dental prosrthesis wearers Proper diagnosis of denture stomatitis
Exclusion criteria
No history of antifungal use in the last 6 months Negative medical history for radiotherapy, chemotherapy or immunodeficiency
Outcome results
None listed