Burns And Silver In Children: A comparison of the silver based dressings Aquacell and Acticoat for paediatric burns.

A randomised controlled study of the effect of silver based burns dressings Aquacell and Acticoat on percentage epithelialisation in a paediatric emergency department.

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000451202

Acronym

BASIC

Enrollment

Registered

2009-06-12

Start date

2009-10-31

Completion date

2013-10-31

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to determine whether Aquacell is a superior silver based dressing compared to Acticoat for paediatric burns managed as an outpatient .

Interventions

Aquacel Ag will be applied to the wound bed with a 3cm overlap to allow for the dressing to shrink. Telfa (an absorbent cotton fabric bonded on both sides with perforated non-adherent film) will be placed over the Aquacel Ag and then Hypafix will be used to hold the dressing in place. These patients will not be instructed to moisten the dressing at home. Patients will be reviewed in 3 days after the initial dressing placement. The Hypafix will be removed, and areas of non-adherence will be trimmed and replaced if still considered to be partial thickness and appropriate for outpatient management. Hypafix will then be re-applied. Patients will be reviewed at day 10 with dressing removal and photography to allow percentage epithelialisation to be assessed

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used) (Outcomes Assessor)

Eligibility

Sex/Gender

All

Age

0 to 14 Years

Healthy volunteers

Inclusion criteria

Partial Thickness Burn (blistering and with normal or increased capillary refill) Present to Starship Emergency Department within 24 hours of the burn injury

Exclusion criteria

Superficial epidermal burn (no blistering) Full-thickness burns and Deep Partial-thickness burns Partial-thickness burns > 10% Body surface area Burns to the perineum, genitalia, face, hands or feet (Aquacel Ag contraindicated) Burns over major joints Circumferential Burns Chemical or Electrical burns Allergy to silver Patients referred for evaluation of Non-Accidental-Injury Patients expecting to reside outside Auckland during the 10 day follow-up period.

Outcome results