None listed
Conditions
Brief summary
Purpose of trial is to compare Continuous positive airway pressure (CPAP) versus conventional therapy of inspired postive pressure ventilation with bag valve mask.
Interventions
Continuous postive airway pressure (CPAP) at 10 cm H20 with face mask will be used for patients in acute respiratory distress with clnical diagnosis of acute cardiogenic pulmonary oedema) ACPO. The duration of the treatment will be time transported and treated by paramedics. All other treatments will be cosistant between groups (Glycerine trinitrate (GTN) spray incremental doses every 5 min of 400 mcg up to 1600 mcg sublingual with repreated 1600 mcg every 5 min as long as BP >100 systolic, Frus
Continuous postive airway pressure (CPAP) at 10 cm H20 with face mask will be used for patients in acute respiratory distress with clnical diagnosis of acute cardiogenic pulmonary oedema) ACPO. The duration of the treatment will be time transported and treated by paramedics. All other treatments will be cosistant between groups (Glycerine trinitrate (GTN) spray incremental doses every 5 min of 400 mcg up to 1600 mcg sublingual with repreated 1600 mcg every 5 min as long as BP >100 systolic, Frusemide dose 40 mg increments every 20 min to max 80 mg intravenous)
Sponsors
Tasmanian Ambulance Service department of health and human services
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Age over 18 years Crackles on auscultation of the lungs Breathlessness and increased work of breathing History of ischemic heart disease (IHD) or risk factor contributing to IHD
Exclusion criteria
Other respiratory conditions (particularly asthma and Chronic obstructive pulmonary disease (COPD)
Outcome results
None listed