None listed
Conditions
Brief summary
The purpose of the study is to determine which surgical technique provides the best alignment for total knee replacements The null hypothesis is that all techniques are equally good.
Interventions
Patients will undergo total knee replacement (TKR) using one of three methods:
1. extramedullary alignment (surgery uses a jig placed on the outside of the leg to determine cut placement)
2. intramedullary alignment surgery uses a jig placed on a rod sitting in the medullary canal of the tibia to determine cut placement)
3. Computer assisted surgery (CAS) alignment, surgery uses a jig, placement of which is determined by computer reconstruction of the leg to determine cut placement)
The surger
Patients will undergo total knee replacement (TKR) using one of three methods: 1. extramedullary alignment (surgery uses a jig placed on the outside of the leg to determine cut placement) 2. intramedullary alignment surgery uses a jig placed on a rod sitting in the medullary canal of the tibia to determine cut placement) 3. Computer assisted surgery (CAS) alignment, surgery uses a jig, placement of which is determined by computer reconstruction of the leg to determine cut placement) The surgery takes 1-2 hours for all the procedures.
Sponsors
Riaz Khan
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
Primary total knee replacement for varus osteoarthritis
Exclusion criteria
Patients will be excluded from the trial for tibial deformity (including past fracture or high tibial osteotomy) or valgus deformity.
Outcome results
None listed