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3-point compression ultrasonography performed by consultant emergency physicians in the emergency department for the diagnosis of proximal lower extremity deep venous thrombosis

The utility of 3-point compression ultrasonography performed by consultant emergency physicians for the diagnosis of proximal lower-extremity deep venous thrombosis in symptomatic patients presenting to the emergency department, compared with reference-standard formal full-leg duplex ultrasonography performed in the radiology department

Status
Terminated
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000359235
Acronym
Nil
Enrollment
300
Registered
2009-05-26
Start date
2009-05-11
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to evaluate the overall usefulness of 3-point compression ultrasonosgraphy performed by emergency physicians in the emergency department for the diagnosis of proximal lower-extremity deep venous thrombosis. In order to be useful, the examination should be accurate, fast, technically adequate and easy to learn. Therefore, this study will examine the accuracy, rapidity and technical adequacy of the examination, as well as the learning curve emergency physicians experiencing with the examination. We hypothesise that the examination will be useful.

Interventions

3-point compression ultrasonography for the diagnosis of proximal lower-extremity deep venous thrombosis performed by emergency physicians in the emergency department. This ultrasonographic examination only involves evaluation of the compressibility of specific veins at three sites: the common femoral vein just below the inguinal ligament, the great saphenous vein approximately 3 - 4cm distal to the saphenofemoral junction, and the popliteal vein in the popliteal fossa. It is a brief and sim

3-point compression ultrasonography for the diagnosis of proximal lower-extremity deep venous thrombosis performed by emergency physicians in the emergency department. This ultrasonographic examination only involves evaluation of the compressibility of specific veins at three sites: the common femoral vein just below the inguinal ligament, the great saphenous vein approximately 3 - 4cm distal to the saphenofemoral junction, and the popliteal vein in the popliteal fossa. It is a brief and simple examination which we expect to take less than 10 minutes to perform. Those performing the ultrasonography will be consultant emergency physicians: no doctor or healthcare worker of a lesser experience level will participate.

Sponsors

AProf. Robert Dunn
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Crossover
Primary purpose
Diagnosis
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients presenting to the emergency department with clinical indications of deep venous thrombosis, as determined by their treating emergency department doctor, who are 18 years of age, or older

Exclusion criteria

Lower extremity ultrasonography (US) of the symptomatic limb within the previous 48 hours; The presence of an indwelling femoral vascular catheter or dialysis vascular shunt in the symptomatic limb; An above knee-amputation of the symptomatic limb; The complete inability to access any of the 3 landmarks on the symptomatic limb that are required for the 3-point compression ultrasonographic examination. The general areas in question are the anteromedial aspect of the thigh inferior to the inguinal ligament, and the popliteal fossa; An open wound involving any of the 3 landmarks on the symptomatic limb that are required for the 3-point compression ultrasonographic examination; Allergy to the gel used in the ultrasonographic examination; though this is extremely rare, it has been reported and must be considered.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026