None listed
Conditions
Brief summary
High frequency mechanical strain, as delivered when standing on a whole body vibration (WBV) platform, has been shown to have beneficial effects on weight bearing bone and muscle mass. Improved bone health in older adults from the use of gently vibrating platforms may be possible, but more scientific investigations are required. The role of these devices is poorly understood. This study proposes to investigate the effect of six months of WBV training on BMD, bone geometry and muscle mass and function in older adults; and to examine the dose-response relationship between optimum vibration protocols and bone mineral, bone geometry and muscle mass. The study will be a randomized controlled trial. The primary outcome measures will be BMD and muscle mass measured with dual energy X-ray absorptiometry (DEXA) and bone geometry and muscle area of lower limbs measured using peripheral quantitative computer tomography (pQCT).
Interventions
a) Whole Body Vibration (WBV) uses high frequency stimuli which are generated by a vibrating platform transmitted through the body where they load the bone and stimulate muscle.
b) participants stand upright with knees either soft or locked. Participants will be randomized into one of the groups (ie locked kness ot soft knees) according to a randomisation plan generated from www.randomization.com by a researcher not directly involved in the study. The trainers will monitor the knee position thro
a) Whole Body Vibration (WBV) uses high frequency stimuli which are generated by a vibrating platform transmitted through the body where they load the bone and stimulate muscle. b) participants stand upright with knees either soft or locked. Participants will be randomized into one of the groups (ie locked kness ot soft knees) according to a randomisation plan generated from www.randomization.com by a researcher not directly involved in the study. The trainers will monitor the knee position throughout the training session. An overhead transparency drawn with the correct knee angle for soft knees will be used to enable the correct knee angle is maintained throughout each training session. c) the duration and frequency of whole body vibration intermittent exposure is 20 minute (alternating 1 minute vibration, 1 minute off; 10 min total vibration exposure) sessions 3 times a week for 26 weeks.
Sponsors
University of Sydney
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Adults aged 50 & older (women to be post menopausal for at least one year), normal nutritional status, no cognitive impairment, able to stand unaided for at least 20 minutes and willing to participate in the study. If currently on medications for osteoporosis e.g. bisphosphonates, Vitamin D, calcium, maintain for the duration of the study, and if osteoporosis medication has not changed within the past two months.
Exclusion criteria
Contraindications to resistance exercise testing, contraindications to vibration training, diseases related to bone metabolism other than osteoporosis (e.g. hyperthyroidism) and terminal illness.
Outcome results
None listed