Does the peri-articular injection of corticosteroid during knee replacement surgery result in reduced pain and improved knee function ?

The role of intra-operative peri-articular steroid injection in reducing post-operative pain and improving knee function after total knee arthroplasty: a prospective randomised controlled trial.

Status

Not yet recruiting

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000345280

Enrollment

150

Registered

2009-05-25

Start date

2009-06-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to determine if injecting corticosteroid into the knee during total knee replacement results in improved pain and function (in the short to medium term).

Interventions

Prospective randomised trial comparing pain/functional outcomes between the intra-operative peri-articular injection of either 0, 20 mg or 40 mg of triamcinolone acetonide

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Healthy volunteers

Inclusion criteria

patients undergoing total knee arthroplasty

Exclusion criteria

diabetes mellitus requiring insulin replacement corticosteroid allergy immunocompromise chronic regional pain syndromes workers compensation cases

Outcome results