None listed
Conditions
Brief summary
The purpose of this study is to evaluate the effects of left atrial pacing on the overall hemodynamic response in patients receive cardiac resynchronization therapy. It is believed that left atrial pacing may improve hemodynamics.
Interventions
Left atrial pacing using a left atrial lead and electrophyisiology heart catheter stimulation for 30 seconds. This will be compared to the hemodynamic effects of traditional right atrial (RA)pacing using the implanted RA lead. Several pacing interventions (using a combination of right atrial and left atrial pacing combinations) and will be performed using a dedicated 4-channel pacing system. For each pacing intervention, the optimal timing setting will be determined as calculated by a real-time
Left atrial pacing using a left atrial lead and electrophyisiology heart catheter stimulation for 30 seconds. This will be compared to the hemodynamic effects of traditional right atrial (RA)pacing using the implanted RA lead. Several pacing interventions (using a combination of right atrial and left atrial pacing combinations) and will be performed using a dedicated 4-channel pacing system. For each pacing intervention, the optimal timing setting will be determined as calculated by a real-time cardiac hemodynamic monitoring system. Each pacing intervention will be evaluated based on the resulting hemodynamic response. The entire pacing intervention will take 30 minutes and is administered only once in an acute setting.
Sponsors
St Jude Medical
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
undergoing cardiac resynchronization therapy (CRT) implantation able to consent
Exclusion criteria
no persistant or permanent atrial fibrillation (AF) no recent myocardial infarction (MI) or Cardiac surgery
Outcome results
None listed