Patients on fluorouracil and folinic acid chemotherapy: a cohort study focused on oral mucositis.

Colorectal adenocarcinoma patients followed through their chemotherapy for assessing oral mucositis manifestations.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12609000339257

Acronym

5FU-OM study

Enrollment

Registered

2009-05-25

Start date

2007-12-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The main purpose of the trial is to gather information on occurrence, features and severity of oral mucositis related to a 5-FU and folinic acid chemotherapy protocol applied to a cohort of patients with a solid malignant tumor - colorectal adenocarcinoma.

Interventions

Observational study on the frequency and severity of chemotherapy induced oral mucositis manifestations in a cohort of patients with colorectal cancer treated with a fluorouracil plus folinic acid chemotherapy, during the whole chemotherapy protocol, i.e. 7 months. Chemotherapy induced oral mucositis is characterized by a range of symptoms varying from mild burning sensation up to extensive ulcerations that preclude patients from feeding and drinking, demanding hospitalization. The patients to b

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients surgically treated of a colorectal adenocarcinoma and elected to receive chemotherapy composed of fluorouracil and folinic acid according to a bolus delivering regimen

Exclusion criteria

Patients that do not match the inclusion criteria will not be eligible for the study. Adittionally patients that suffer any modification in their chemotherapy protocol during the course of the trial will be also excluded.

Outcome results