None listed
Conditions
Brief summary
Study hypothesis: The human body has a natural capacity to regenerate and to grow new tissue to fill an empty space. This study applies a new method of breast reconstruction using the patient’s own regenerative capacity. This method provides an alternative to current breast reconstruction techniques and also an opportunity for patients who have no other option for reconstruction. In the operation an acrylic spacer, shaped according to the breast defect, will be placed under the skin of the chest wall to allow a piece of fat with a blood supply to grow over time (3-6 months) to fill the space created by the acrylic spacer. The small piece of fat with a blood supply will be sourced from well-known existing donor sites for breast reconstruction (chest or abdomen). Because the amount of tissue is small the expected donor site scars will be smaller compared with the usual reconstruction methods.
Interventions
Breast reconstruction in an implanted acrylic spacer using the body's own ability to grow new tissue to fill the empty space provided by acrylic spacer over a perioid of 3 to 6 months.
Sponsors
Microsurgical Research Foundation
Study design
Allocation
Non-randomised trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Breast asymmetry, unlikely suitable for other reconstructive flap methods.
Exclusion criteria
Previous chest wall irradiation
Outcome results
None listed