Does prewarming children improve outcomes in children with cerebral palsy having major lower limb surgery?

A randomised study assessing the effect of prewarming on outcomes of children with cerebral palsy undergoing orthopaedic surgery to prevent hypothermia

Status

Terminated

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000297224

Enrollment

Registered

2009-05-18

Start date

2010-02-10

Completion date

2011-08-22

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a controlled single-blind randomised study assessing the effect of prewarming on outcomes of patients with severe cerebral palsy undergoing major orthopaedic surgery. The study objectives are to assess the effect of prewarming participants prior to anaesthesia with regard to: i) Avoiding hypothermia. ii) Duration of recovery from anaesthesia. iii) Amount of surgical blood loss. iv) Rate of wound infections.

Interventions

The intervention is for patients to lie in a bed and be prewarmed with a forced air warming blanket set at 40 degrees for one hour prior to induction of anaesthesia.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

5 Years to 20 Years

Healthy volunteers

Inclusion criteria

1)Children with severe cerebral palsy undergoing elective bilateral femoral valgus derotational osteotomies 2) Children aged between 5 -20 years 3) Any weight

Exclusion criteria

1) Any contraindication to inhaled anaesthetic agents (desflurane/nitrous oxide) (eg: malignant hyperthermia) 2) Severe comorbidities that require postoperative admission to intensive care. 3) Contraindications to epidural anaesthesia (eg: iatrogenic or pathological coagulopathy or platelet dysfunction, local Sepsis, parental refusal to consent) 3) Ambient room temperature > 28 degrees in the pre-surgical centre

Outcome results