None listed
Conditions
Brief summary
This clinical trial is designed to test whether the three commonly used oral steroid treatment regimes for croup, are equally effective. Children will receive one of the three treatments, decided by a random process, and their improvement and outcomes monitored by investigators who are blinded to the treatment received.
Interventions
Group 1 - oral prednisolone 1 mg/kg oral liquid, single dose;
Group 2 - oral dexamethasone 0.15 mg/kg oral liquid, single dose;
Sponsors
Dr Colin Parker
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
6 Months to 10 Years
Healthy volunteers
No
Inclusion criteria
Clinical diagnosis of croup Age 6 months to 10 years Weight no more than 20 kg Parents contactable by telephone Parents speak English
Exclusion criteria
High clinical suspicion of an alternative diagnosis, Known allergy to prednisolone or dexamethasone, Immunosuppressive disease or treatment, Steroid therapy in past 14 days, Enrolment in this study in past 14 days
Outcome results
None listed