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1. ASPECT - ASIA PACIFIC EVALUATION OF CHEST PAIN TRIAL An observational study of the diagnostic utility of a biomarker panel in the assessment of patients presenting to asia-paciifc hospitals with chest pain of possible cardiac origin

1. ASPECT - ASIA PACIFIC EVALUATION OF CHEST PAIN TRIAL An observational study of the diagnostic utility of a biomarker panel in the assessment of patients presenting to asia-paciifc hospitals with chest pain of possible cardiac origin

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12609000283279
Enrollment
3582
Registered
2009-05-15
Start date
2007-11-06
Completion date
2010-07-31
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a prospective observational study of the diagnostic utility of the "Triage" multi-marker point of care blood testing device to measure the levels of the cardiac markers Troponin I, Creatine Kinase MB and myoglobin: - in people presenting to the Emergency Deprtment with chest pain of probable caridac origin. Blood samples will be taken and tested on arrival and again at 2 hours. Participants will undergo risk evaluation by a means of a set series of questions. Participants will recieve a phone call at 45 days, 6 months and 1 year post discharge to record any major adverse cardiac event (MACE) they may have experienced.

Interventions

ASPECT: The Triage multi-marker panel consists of measurements of Troponin I, Creatine Kinase MB (CKMB) and myoglobin levels using a point of care testing device for blood samples taken from people who present with probable ischaemic chest pain to the Emergency Department. A sample is tested on arrival and again 2 hours later.

Sponsors

Inverness Medical Innovations
Lead SponsorCommercial sector/Industry

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Adults presenting to the trial hospital Emergency Department with chest pain of possible cardiac origin

Exclusion criteria

Age < 18 years. Non-resident in country of recruitment. Patients for whom follow-up will not be possible either due to lack of onward contact address or because they will be overseas. Unable or unwilling to consent

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 6, 2026