The IDEAL Study: a clinical trial of the timing of kidney dialysis initiation on survival in subjects with chronic kidney disease.

Initiating Dialysis Early and Late (IDEAL) Study. A study reviewing the effect of the timing of dialysis initiation on survival in subjects with chronic kidney disease.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000266268

Acronym

IDEAL Study

Enrollment

800

Registered

2009-05-14

Start date

2000-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It has been suggested that dialysis should be commenced early, in subjects with progressive chronic kidney disease, in order to prevent illness and complications however this had never been proven. The IDEAL study was designed to determine when is the best time to commence kidney dialysis for the very first time. 8 Centers are participating in New Zealand. 24 Centers are participating in Australia.

Interventions

Subjects randomized to the Early dialysis initiation: commence dialysis as soon as possible with a target glomerular filtration rate (GFR) of 10-14 ml/min/1.73m^2. Dialysis type and regimen used (haemodialysis or peritoneal dialysis) is determined by the caring renal physician.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Age greater than 18 years. Progressive chronic kidney disease. GFR between 10-20ml/min/1.73m^2.

Exclusion criteria

Significant cancer. Planned live renal transplant in the next 12 months.

Outcome results