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The effect of a combined aerobic and resistance exercise program on people with Type 2 diabetes and peripheral neuropathy

The effect of a combined aerobic and resistance exercise program on strength, function and proprioception in people with diabetic peripheral neuropathy

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000264280
Enrollment
30
Registered
2009-05-14
Start date
2009-04-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This research aims to investigate the effects of a combined aerobic and resistance exercise program on measures of strength, function and sensation in those with Type 2 diabetes and peripheral neuropathy. It will also aim to explore the safe prescription of exercise for these individuals, its effects on levels of quality of life, and to identify the potential barriers and enablers to a sustained exercise program.

Interventions

The intervention is a 12-week combined aerobic and resistance exercise program. This will require participants to attend the Health and Fitness Exercise Clinic at the School of Health Sciences at the University of South Australia twice weekly to perform a combination of aerobic and resistance activities at a moderate intensity. All programs will be individually designed and monitored, and supervised by an accredited exercise physiologist. Each session will be 1 hour in duration. During each ses

The intervention is a 12-week combined aerobic and resistance exercise program. This will require participants to attend the Health and Fitness Exercise Clinic at the School of Health Sciences at the University of South Australia twice weekly to perform a combination of aerobic and resistance activities at a moderate intensity. All programs will be individually designed and monitored, and supervised by an accredited exercise physiologist. Each session will be 1 hour in duration. During each session participants will be required to perform 20minutes of moderate intensity low weight bearing exercise such as stationary cycling and rowing. Participants will also be required to perform a progressive resistance training program ranging from 50-85% 1RM (repetition maximum). A combination of 8 exercises will be performed for 8-10 repetitions over 2 sets. The exercises will include a bench press, leg extension, leg curl, calf raise, biceps curl, triceps extension, lateral pull-down and a shoulder press.

Sponsors

Rebecca Nolan
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

participants will be required to obtain a medical clearance from their General Practitioner prior to the commencement of the study. Participants will be aged between 50-70 years, have had Type 2 diabetes for greater than 6 months controlled by diet and/or hypoglycaemic agents, have peripheral neuropathy as diagnosed by their medical officer, and must be sedentary.

Exclusion criteria

participants will be excluded if they have Type 1 diabetes or Type 2 diabetes controlled by insulin, a history of recurrent hypoglycaemic episodes within the part 6-months, the presence of any co-morbidities which would inhibit physical activity, and the presence or history of any ulceration, amputation or gangrene.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026