Prospective risk assessment of bacteraemia and other infectious complications in patients undergoing Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)

Prospective risk assessment of bacteraemia and other infectious complications in patients undergoing Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of mediastinal masses

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12609000244202

Enrollment

Registered

2009-05-12

Start date

2009-01-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We hypothesize that bacteraemia occurs in a small proportion of people following needle puncture of the tracheal wall during Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of mediastinal lymph nodes. The purpose of the study is to confirm the proportion, and also to identify the likely bacteriologic agents. This will allow appropriate guidelines of use of antibiotic prophylaxis and choice of empiric antibiotic therapy for those developing clinical infection following EBUS-TBNA

Interventions

We will determine the proportion of people developing bacteraemia following EBUS-TBNA through performance of blood cultures, to be taken prior to and immediately after performance of EBUS-TBNA. Observation of participants will cease after collection of peripheral blood immediately after the procedure. The study will be conducted over a six month period.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Patients undergoing EBUS-TBNA for investigation of mediastinal and/or hilar masses

Exclusion criteria

fever clinically evident infection (anywhere) known bacteraemia antibiotic treatment within 1 week of procedure

Outcome results