Omega-3 oil and bone health

Plant-based omega-3 fatty acid supplementation, acceptability and efficacy for bone health

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000238279

Enrollment

Registered

2009-05-11

Start date

2008-12-01

Completion date

2009-10-01

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Omega-3 oils are known to have benefits for joints, skin and the circulation. There are reasons to believe that they may help improve bone health in people with low bone density. This study aims to examine the safety, effectiveness and acceptability of an omega-3 oil, docosohexanoic acid (DHA) when given for 1 year in combination with calcium and vitamin D.

Interventions

1 year of oral docosohexanoic acid (DHA) 400 mg daily. DHA is of algal origin (i.e. suitable for vegetarians/vegans). All participants will receive oral vitamin D3 1000 IU daily with calcium carbonate 1200 mg daily

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

DEXA BMD T-score between -1.0 and -2.4 (inclusive) abbreviations as noted above: Bone Mineral density (BMD); Dual Energy X-ray Absorptiometry (DEXA)

Exclusion criteria

already on antiresorptive agents

Outcome results