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Randomised trial comparing controlled oxygen therapy with high-flow oxygen therapy in the treatment of patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in the pre-hospital setting

Randomised trial comparing controlled oxygen therapy with high-flow oxygen therapy in the treatment of patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in the pre-hospital setting

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000236291
Enrollment
150
Registered
2009-05-11
Start date
2006-07-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Purpose to determine if different oxygen therapies for patients having AECOPD in the pre-hospital setting have different outcomes (ie. Mortality, length of hospital stay, requirement for ventilation, difference ABGs)

Interventions

controlled oxygen therapy to maintain oxygen saturations between 88-92% using nasal prongs and mask oxygen with nebulization of medication done by handheld air driven compressor for the duration of the ambulance transport once off treatment pre hospitally

Sponsors

Associate Professor Richard Wood-Baker
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
35 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Confirmed Diagnosis COPD, acute respiratory symptoms, Transport and treatment by Tasmanian Ambulance Staff

Exclusion criteria

Asthma patients

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 30, 2026