Dose response study of folic acid supplementation in New Zealand women.

Effect of mandatory folic acid fortification policy on folate status of New Zealand women of childbearing age.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000215224

Enrollment

120

Registered

2009-04-28

Start date

2008-08-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This project is being undertaken to determine the effect of folic acid bread fortification on blood folate concentrations in New Zealand women of childbearing age. We will be measuring the response of blood folate to a daily folate vitamin supplement of either 140mcg, 400mcg, and comparing these results to a placebo group.

Interventions

Participants will be randomized to receive a daily, oral supplement containing either 140mcg or 400mcg of folic acid for 10 months.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy New Zealand women of childbearing age.

Exclusion criteria

Women who were pregnant in the previous year, or who are currently pregnant or planning a pregnancy, taking medications that may affect folate metabolism, or chronic disease.

Outcome results