None listed
Conditions
Brief summary
The impact of blood loss during liver resection and the need for perioperative blood transfusions have been shown to negatively impact perioperative morbidity and mortality as well as long term outcomes. The objective of this study is To compare the perioperative outcomes of partial hepatectomy using hemihepatic vascular inflow occlusion, portal vein inflow occlusion. and Pringle maneuver.
Interventions
Hemihepatic Vascular Inflow Occlusion group (In hemihepatic vascular inflow occlusion, the portal vein, hepatic artery, and bile duct were dissected in the hilum by lowering the liver plate. Either the right or left portal pedicle was isolated en bloc and was controlled with a tourniquet or Santinsky clamp. The estimated duration is around 30 minutes.)
Portal Vein Inflow Occlusion group (In portal vein inflow occlusion, the portal vein was isolated and occluded with a tourniquet. The estimated d
Hemihepatic Vascular Inflow Occlusion group (In hemihepatic vascular inflow occlusion, the portal vein, hepatic artery, and bile duct were dissected in the hilum by lowering the liver plate. Either the right or left portal pedicle was isolated en bloc and was controlled with a tourniquet or Santinsky clamp. The estimated duration is around 30 minutes.) Portal Vein Inflow Occlusion group (In portal vein inflow occlusion, the portal vein was isolated and occluded with a tourniquet. The estimated duration is around 30 minutes.)
Sponsors
The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
16 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
(1) Elective liver resection; (2) No other concomitant major surgical procedures, such as bowel or bile duct resection; (3) Compensated cirrhosis with Child-Pugh class A or B.
Exclusion criteria
1. Contralateral hepatic resection was required; 2. Total or selective vascular inflow/outflow occlusion was required because of tumor extent
Outcome results
None listed