None listed
Conditions
Brief summary
Weight gain has been associated with increased inflammation, and fish oil supplementation has been shown to possess anti-inflammatory properties. This study is investigating whether fish oil supplementation may reduce inflammation and assist weight loss and weight loss maintenance
Interventions
A very low Kilojoule (kJ) diet (VLCD) of 3,000 kJ, using meal replacements, will be followed for 4 weeks. The meal replacements will be supplied to participants as part of the study. Participants will also consume, by mouth, 6 x 1g/day fish oil capsules composed of 270mg Docosahexaenoic Acid (DHA) and 70mg Eicosapentaenoic Acid (EPA) /capsule. Participants then progress to weight maintenance for 10 weeks and continue to take the 6 x 1g/day fish oil capsules.
Participants receive 1 x 20 min
A very low Kilojoule (kJ) diet (VLCD) of 3,000 kJ, using meal replacements, will be followed for 4 weeks. The meal replacements will be supplied to participants as part of the study. Participants will also consume, by mouth, 6 x 1g/day fish oil capsules composed of 270mg Docosahexaenoic Acid (DHA) and 70mg Eicosapentaenoic Acid (EPA) /capsule. Participants then progress to weight maintenance for 10 weeks and continue to take the 6 x 1g/day fish oil capsules. Participants receive 1 x 20 minutes per week individual education sessions on dietary modification and behaviour change for the four weeks of weight loss.
Sponsors
The University of Newcastle
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Body Mass Index (BMI) between 30 and 40 Can consume fish Can swalllow capsules
Exclusion criteria
BMI >40 Diabetic Already consuming fish oil capsules or more than 2 oily fish meals/week Has inflammatory condition
Outcome results
None listed