Detection of Bony Metastases: Preliminary Study of 18F-Fluoride Positron Emission Tomography/Computed Tomography (PET/CT)

Is 18F-Fluoride Positron Emission Tomography/Computed Tomography (PET/CT) a beneficial test in detecting bony metastases in cancer patients with high risk of metastasis or suspicious/equivocal findings for bony metastasis by conventional studies?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12609000120279

Enrollment

300

Registered

2009-02-19

Start date

2008-08-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The current study is to assess the accuracy and impact of a new examination (18F-Fluoride PET/CT) for detecting bony metastasis in cancer patients with high risk of bony metastasis or suspicious/equivocal findings for bony metastasis by conventional studies. The hypothesis to be confirmed in the current study is that the new examination (18F-Fluoride PET/CT) is beneficial for these patients and can give clinical oncologists more accurate diagnosis.

Interventions

18F-Fluoride PET/CT is a noninvasive diagnostic imaging examination which involves intravenous injection of an isotope tracer (with a dosage of 7.0 mCi +/- 10%) followed by a whole-body scan of approximate 20 minutes (with the patient in the supine position). The participant will receive this examination one time which will take a total duration of less than 2 hours.

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Diagnosis

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

1. patients with histological diagnosis of breast cancer, head and neck cancer, lung cancer, gynecological cancer, genitourinary cancer, or colorectal cancer 2. high risk of or suspicious/equivocal findings for bony metastasis by conventional studies

Exclusion criteria

1. Patients with more than one type of cancer 2. patients with pregnancy or breast-feeding

Outcome results