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Effect of Vibration Training and Detraining on Muscle Function in Patients with Cystic Fibrosis

Effect of Vibration Training and Detraining on Muscle Function in Patients with Cystic Fibrosis: A Pilot Efficacy Trial.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12609000090213
Enrollment
12
Registered
2009-02-10
Start date
2008-07-31
Completion date
2008-08-27
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It is well known that certain exercises can help increase muscle strength, power and endurance, but a lot of these exercises can prove hard to complete for some people with cystic fibrosis (CF). Recent research has been looking at this new form of exercise (vibration training), and it’s been proven to have positive impacts on muscle in animals and certain human populations. It has not yet been tested with CF patients. It is hoped that the vibration platform training will not only benefit muscle strength and power, but also respiratory function and overall quality of life in CF patients.

Interventions

whole body vibration training. Patients will be required to stand on the vibration platform with a knee angle of 150 degrees, 3 days a week for four weeks. Frequency is 20Hz for the first 2 weeks, and 22 Hz for the remaining 2 weeks, with a 1mm amplitude maintained throughout. Patients wear socks while on the platform, and each training session goes for 30 minutes in total, with intermittent exposure of 1 minute vibration, 1 minute rest (standing on the platform). The proceeding washout period i

whole body vibration training. Patients will be required to stand on the vibration platform with a knee angle of 150 degrees, 3 days a week for four weeks. Frequency is 20Hz for the first 2 weeks, and 22 Hz for the remaining 2 weeks, with a 1mm amplitude maintained throughout. Patients wear socks while on the platform, and each training session goes for 30 minutes in total, with intermittent exposure of 1 minute vibration, 1 minute rest (standing on the platform). The proceeding washout period is also four weeks.

Sponsors

Faculty of Health Sciences, The University of Sydney
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Crossover
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
8 Years to No maximum
Healthy volunteers
No

Inclusion criteria

patients with cystic fibrosis aged 8 years or older

Exclusion criteria

*severe cystic fibrosis (CF) (FEV1 < 40% predicted) *inability to stand unaided for 30 min *long bone or vertebral fracture in past 6 months *past/present history of osteoarthritis *CF liver disease with portal hypertension, neuropathy or myopathy *Vitamin D deficiency (25-hydroxyvitamin D) <39 nmol/L (in past 3 months).

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026