None listed
Conditions
Brief summary
It is well known that certain exercises can help increase muscle strength, power and endurance, but a lot of these exercises can prove hard to complete for some people with cystic fibrosis (CF). Recent research has been looking at this new form of exercise (vibration training), and it’s been proven to have positive impacts on muscle in animals and certain human populations. It has not yet been tested with CF patients. It is hoped that the vibration platform training will not only benefit muscle strength and power, but also respiratory function and overall quality of life in CF patients.
Interventions
whole body vibration training. Patients will be required to stand on the vibration platform with a knee angle of 150 degrees, 3 days a week for four weeks. Frequency is 20Hz for the first 2 weeks, and 22 Hz for the remaining 2 weeks, with a 1mm amplitude maintained throughout. Patients wear socks while on the platform, and each training session goes for 30 minutes in total, with intermittent exposure of 1 minute vibration, 1 minute rest (standing on the platform). The proceeding washout period is also four weeks.
Sponsors
Study design
Eligibility
Inclusion criteria
patients with cystic fibrosis aged 8 years or older
Exclusion criteria
*severe cystic fibrosis (CF) (FEV1 < 40% predicted) *inability to stand unaided for 30 min *long bone or vertebral fracture in past 6 months *past/present history of osteoarthritis *CF liver disease with portal hypertension, neuropathy or myopathy *Vitamin D deficiency (25-hydroxyvitamin D) <39 nmol/L (in past 3 months).