None listed
Conditions
Brief summary
This study aims to determine the lens parameters in orthokeratology lenses that allow manipulation of peripheral refraction in adult myopes. Additionally, relationships between corneal topography and peripheral refraction changes induced by orthokeratology lenses will be investigated.
Interventions
Adult subjects with myopia will wear orthokeratology lenses (BE design; Boston XO2 material) in both eyes on an overnight basis, only worn while asleep, for a 6 week period. Baseline measurements will be obtained from the first two weeks of lens wear. All subjects will then be asked to cease lens wear for the following 2 weeks. All subjects will then be asked to wear different orthokeratology lenses for the subsequent 2 weeks on an overnight basis only while asleep. The lens design worn duri
Adult subjects with myopia will wear orthokeratology lenses (BE design; Boston XO2 material) in both eyes on an overnight basis, only worn while asleep, for a 6 week period. Baseline measurements will be obtained from the first two weeks of lens wear. All subjects will then be asked to cease lens wear for the following 2 weeks. All subjects will then be asked to wear different orthokeratology lenses for the subsequent 2 weeks on an overnight basis only while asleep. The lens design worn during the second period of wear will also be of BE design and made from Boston XO2 material, however the lens parameters will be altered. In one eye, the lens edge lift angle will be reduced to create a tighter peripheral lens fit while the other eye will have the lens optic zone diameter decreased from 6mm to 5mm. The measurements from this second lens wear period will be compared with those obtained from baseline lens wear.
Sponsors
Associate Professor Helen Swarbrick
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
Participants will require to have a myopic refractive error between -0.75 to -4.00D and less than 1.50D with-the-rule astigmatism. Participants must have good general and ocular health, no medications which may influence ocular health and no history of rigid contact lens wear.
Exclusion criteria
Potential subjects will not be enrolled if they show any contraindications for rigid contact lens wear, ocular pathology or active ocular surface disease that would preclude contact lens wear.
Outcome results
None listed