None listed
Conditions
Brief summary
The primary purpose of the study is to compare two commonly performed anti-reflux surgical procedures and to assess whether there is any difference in long-term patient satisfaction between these two procedures
Interventions
A Laparoscopic Nissen fundoplication involves repair of the crural defect in the diaphragm, together with a 360 degree wrap of the fundus of the stomach around the lower end of the intra-abdominal oesophagus. This is performed laparoscopically and is a single intervention
Sponsors
Groote Schuur Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Inclusion criteria 1. PPI(proton pump inhibitor) dependent, erosive reflux, OR 2. Volume reflux not responsive to PPI, AND 3. Willingness to undergo long-term follow-up AND 4. Willingness to sign informed consent 5. Abnormal motility included provided an absence of apersitalsis (achalasia)
Exclusion criteria
Exclusion Criteria 1. Esophageal stricture, or 2. Extra-esophageal symptoms unresponsive to PPI, or 3. Previous abdominal or gastric surgery, or 4. Surgically unfit patients, or 5. Refusal to undergo long-term follow-up, or 6. Refusal or inability to sign informed consent, or 7. Age less than 18 years
Outcome results
None listed