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Circadian disruption after anaesthesia and surgery in patients undergoing cardiac surgery.

Circadian disruption after anaesthesia and surgery in patients undergoing cardiac surgery.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12608000640303
Enrollment
50
Registered
2008-12-17
Start date
2006-12-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Sleep, controlled by the sleep homeostat and the circadian clock, is essential. In the hospital environment, sleep can be disrupted. This disruption may be attributable to an effect on the sleep homeostat, the circadian clock, or both. The consequences of sleep disruption due to hospitalisation, surgery and anaesthesia may include delayed post-operative recovery. Here, we measure sleep/ wake cycles, mood states and two different markers of circadian rhythms in a surgical population to determine any changes that may occur in the hospital environment.

Interventions

Patients undergoing cardiac surgery have their sleep/ wake cycles actigraphically measured, their core body temperature rhythms and salivary melatonin measured and recorded and their mood assessed. This takes place in three seperate stages, each a week long. They are monitored pre-operatively, post-operatively in hospital and post-discharge.

Sponsors

University of Auckland
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All patients presenting for elective bypass cardiac surgery

Exclusion criteria

Refusal, non-bypass surgery, patient requiring Magnetic Resonance Imaging at any stage during treatment, congenital heart disease

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026