The effect of Sigvaris below-knee light graduated compression stockings on lower limb venous blood flow in seated adults

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000620325

Enrollment

Registered

2008-12-08

Start date

2008-05-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Prolonged seated immobility at work and with long distance air travel is now recognised to be associated with an increased risk of deep vein thormbosis (DVT) through a reduction in lower limb venous blood flow. Graduated compression stockings represent the preferred approach to improve lower limb venous blood flow, thereby reducing the risk of DVT associated with seating seated during long distance travel or whilst at work. The effect of Sigvaris below-knee light graduated compression stockings on lower limb venous blood flow when subjects are stationary in different positions is unknown. In particular, it is uncertain if the stockings have a direct ability to increase venous blood velocity (speed) in the seated position. If it's use is shown to have a direct effect on the venous blood flow in seated subjects, compared to without a stocking, then it would be reasonable to assume that the associated risk of DVT would be reduced. Study hypothesis: that Sigvaris below knee light graduated compression stockings increase venous blood velocity recordings in the deep vein system of the lower limb (the superfical femoral vein is a deep vein) when assessed on Duplex doppler ultrasound scanning, compared with not wearing a stocking.

Interventions

The effect of below knee graduated compression stockings in adults with normal circulation on venous volume flow after 10 minutes in each of the positions of lying supine, sitting and standing upright

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Able to provide informed consent Ages between 18 to 65 years.

Exclusion criteria

History of current or previous deep vein thrombosis History of current or previous significant peripheral circulation impairment, such as peripheral artherosclerosis, lymphoedema, congestive cardiac failure, or vasculitis. Evidence on physical examination of perpheral vascular compromise.

Outcome results