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effects of rhinoplasty on nasolacrimal duct

assessment of rhinoplasty effects on tear passage time through nasolacrimal duct using chloramphenicol eye drop bitter taste test

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12608000552381
Enrollment
74
Registered
2008-10-30
Start date
2005-01-20
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Rhinoplasty is one of the most common cosmetic surgeries. Lateral osteotomy is one of the surgical methods in rhinoplasty. There are several methods to determine the tear passage time through nasolacrimal duct (NLD) such as dacryocystography, dacryoscintigraphy, Taste test, etc. One of the useful tests which can be used for determining of tear passage through NLD is dripping of chloramphenicol drop in the eye and recording the passage time by its bitter taste perception by the patient. It should be pointed out that this test is easy to do, inexpensive, accessible, and safe. there is a controversy in the effects of rheinoplasty on naso lacrimal duct system. In this clinical trial study (before and after intervention), 37 patients (74 eyes) were examined. The chloramphenicol taste test was done one week before and one week, one month, three months, six month after Rhinoplasty. All the results have been statistically analyzed through paired T and other statistic test.

Interventions

closed rhinoplasty with lateral osteotomy and intranasal incicion over the inferior turbinate using 4mm osteotome with lateral guide

Sponsors

mohammad ebrahim yarmohammadi
Lead SponsorIndividual

Study design

Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
19 Years to 37 Years
Healthy volunteers
No

Inclusion criteria

1-indication of rhinoplasty by otolaryngologists 2-no evidence of nasolacrimal duct obstruction before surgery in history,examinations,scintigraphy,nasolacrimal duct irrigation by normal saline,chloramphenicol eye drop bitter taste test

Exclusion criteria

1-no sensation of taste in pre-surgery test 2-any evidence of lacrimal system disease in history ,examinations,scintigraphy

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026