Health benefits of low fat dairy in overweight but healthy individuals

Dietary intervention trial of cardiometabolic health benefits of low fat dairy consumption in healthy but overweight adults.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000538347

Enrollment

100

Registered

2008-10-24

Start date

2008-10-27

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of our research is to evaluate the health benefits of regular low fat dairy consumption by determining the relationship between consumption of low fat dairy and markers of cardiovascular and metabolic (cardiometabolic) health which include body composition (waist circumference, % body fat, body weight), blood lipids, insulin sensitivity, C-reactive protein, bone mineral density, arterial compliance, blood pressure and resting metabolic rate. Hypothesis: Daily consumption of 4+ serves of low fat dairy over 12 months will improve indices of body composition and cardiometabolic risk factors. Subjects will be recruited at two sites, Adelaide, Australia (n=50) and Winnepeg, Canada (n=50). If eligible volunteers will be randomly allocated to either a high dairy diet (consume 4+ low fat dairy serves daily) or a low dairy diet (consume <1 serve of dairy daily) for 12 months. Outcomes measures including body composition (% body fat, BMI, waist circumference), blood pressure and arterial compliance, insulin sensitivity, blood lipids, C-reactive protein, bone mineral density and resting metabolic rate will be assessed at baseline and at 3, 6 and 12 months.

Interventions

Participants will be randomised to consume a high dairy diet (>4 serves/day, low fat dairy <2% fat) for 12 months. A serve of dairy is based on Australian standardised serves, for example 1 serve of milk is 250mL or 1 cup. Foods will be provided for the volunteers for the duration of the trial. Compliance will be measured using weekly dairy consumption logs and weighed food records (at 0, 3, 6 and 12 months).

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

BMI greater than or equal to 25 but otherwise healthy; able to consume dairy regularly for 12 months; non-smokers; aged 18-75; eat <2 serves of dairy per day

Exclusion criteria

Weight >135kg (DEXA limited); diagnosed diabetes or cardiovascular disease; taking fish oil (>1g/day); irregular use of medications that might interfere with outcomes of the study; females who are pregnant or possibly pregnant (DEXA); smokers.

Outcome results