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A study to evaluate the accuracy of capillary glucose measurement versus colorimetry glucose measurment as methods for determining blood glucose concentration in critically ill patients.

A study to evaluate the accuracy of capillary glucose measurement versus colorimetry glucose measurment as methods for determining blood glucose concentration in critically ill patients.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12608000513314
Enrollment
40
Registered
2008-10-02
Start date
2007-05-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Samples from patients with septic shock or from stable individuals without infection were collected. The correlation between measures was assessed by Pearson’s test, agreement by Bland and Altman test and accuracy by following the Clinical and Laboratory Standard Institute (CLSI) criteria, both in the global sample and in the subgroups on noradrenalin and with signs of tissue hypoperfusion.

Interventions

The objective of this study was to assess the accuracy and clinical agreement between arterial glucose concentration and capillary or central venous measures. A sole set of tests per patient was obtained from all patients in about 5 minutes. Capilary strip, arterial strip, venous and arterial laboratory dosages were performed. Arterial and central venous lines were forcefully used for the samples collection. The catheters lumen was washed with 10mL distilled water, followed by aspiration of 5mL

The objective of this study was to assess the accuracy and clinical agreement between arterial glucose concentration and capillary or central venous measures. A sole set of tests per patient was obtained from all patients in about 5 minutes. Capilary strip, arterial strip, venous and arterial laboratory dosages were performed. Arterial and central venous lines were forcefully used for the samples collection. The catheters lumen was washed with 10mL distilled water, followed by aspiration of 5mL fluids to be disposed of before the collection. Arterial and venous glucose were performed in the Olympus Au640e device, hexochinase G-6-PDHA reagent. For strip determination of glycemia blood from finger pulp lanced with a 26G needle was used. The glucometer available at the institution was the Medisense – FreeStyle Optium® (Abbott Laboratories, USA).

Sponsors

Anesthesiology Deparment - Federal University of São Paulo
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Inclusion criteria were: age = 18 years; presence of arterial and central venous line; intensive glycemic control according to the institution’s protocol and a signed informed consent.

Exclusion criteria

Patients either with diabetes or hemodynamic instability not exclusively related to sepsis were excluded

Outcome results

None listed

Source: ANZCTR · Data processed: Apr 2, 2026