An investigation into the effects of kiwifruit products on in vitro immune cell responses from healthy volunteers

In healthy volunteers, does in vitro incubation of blood-derived immune cells with kiwifruit products have an effect on immune function?

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000494336

Enrollment

Registered

2008-09-30

Start date

2008-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Participants will provide three blood samples of 50 mL each. The first two blood samples from each subject will be used for baseline measurement of immune cell markers, including markers of innate and acquired immune responses. The third blood sample will be incubated with a ZESPRI Gold kiwifruit puree for two hours, after which time immune cell markers will be measured as for the baseline samples. The puree will be added to cells at final dilutions of 1:64, 1:128, 1:256, and 1:512.

Study design

Allocation

Non-randomised trial

Primary purpose

Educational / counselling / training

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

Healthy persons of any gender who have been vaccinated against tetanus within the past year

Exclusion criteria

Pregnant or trying to become pregnant, recent viral illnesses, chronic illnesses affecting the immune system, high/low blood pressure, blood disorders, or taking medication for blood disorders e.g. anticoagulants.

Outcome results