None listed
Conditions
Brief summary
It is hypothesised that consideration of glycaemic index (GI) knowledge and the deliberate use of GI foods to modify low/high GI meals will improve post-prandial glycaemia in patients on insulin pump therapy. Aims: To investigate the effectiveness of clinical dietary advice regarding use of GI knowledge to improve PPG in pediatric patients with T1DM on insulin pump therapy; 1. To assess the clinical effectiveness of the dietary advice regarding the addition of a low GI food to a high GI meal to determine what proportion of the meal needs to contain low GI carbohydrates to improve postprandial glycaemic outcome.
Interventions
use of varying proportions of low glycaemic index food intakes to determine what proportion of the meal needs to be low GI for benefit to glycaemic outcome using CGMS measured blood glucose response and standard bolus dose feature on insulin pump. The criteria for varying glycaemic index intake was based on 25%, 50%, 75% and 100% of the carbohydrate food choices within the meal being low GI in content. An individual test meal is given for breakfast each morning, fasted from the previous night. T
use of varying proportions of low glycaemic index food intakes to determine what proportion of the meal needs to be low GI for benefit to glycaemic outcome using CGMS measured blood glucose response and standard bolus dose feature on insulin pump. The criteria for varying glycaemic index intake was based on 25%, 50%, 75% and 100% of the carbohydrate food choices within the meal being low GI in content. An individual test meal is given for breakfast each morning, fasted from the previous night. The duration of the study is 5 half days within one week. Each subject acts as their own control when comparing the CGMS measured blood glucose response to the differing test meals.
Sponsors
Royal Children's Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
8 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
diagnosed type 1 diabetes > 1 year, established use of insulin pump therapy > 3 months, HbA1c < 8.6%
Exclusion criteria
non-english speaking families, diagnosed eating disorder, concomitant dietary restriction, use of other medication affecting blood glucose levels, presence of diabetes-related complications
Outcome results
None listed