None listed
Conditions
Brief summary
This study aims to demonstrate that, in the long term, a hypocaloric diet supplemented with long chain polyunsaturated fat (LC PUFA) will be more beneficial for weight loss than a control hypocaloric diet for overweight individuals. Outcomes will be compared in those receiving general hypocaloric dietary advice with those receiving the same advice but inclusive of 180g fish/week and LC PUFA (fish oil) supplements. We hypothesise that the intervention will produce positive outcomes for cardiovascular disease risk factors Potential mechanisms for the effect of the diet will be investigated
Interventions
1. Hypocaloric diet for 12 months +daily placebo capsules (1g olive oil)
2. Hypocaloric diet inclusive of 180gfish/week +daily placebo capsules (1g olive oil)
3. 2. Hypocaloric diet inclusive of 180gfish/week + oral fish oil capsules comprising 630 mg/day Long Chain polyunstaurated fatty acids (PUFA) (420 mg Eicosapentaenoic acid (EPA)+ 210 mg docosahexanoic acid (DHA) (Blackmore’s Promega Heart) daily for 12 months.
Dietary intervention comprises dietary education and follow-up provided by a
1. Hypocaloric diet for 12 months +daily placebo capsules (1g olive oil) 2. Hypocaloric diet inclusive of 180gfish/week +daily placebo capsules (1g olive oil) 3. 2. Hypocaloric diet inclusive of 180gfish/week + oral fish oil capsules comprising 630 mg/day Long Chain polyunstaurated fatty acids (PUFA) (420 mg Eicosapentaenoic acid (EPA)+ 210 mg docosahexanoic acid (DHA) (Blackmore’s Promega Heart) daily for 12 months. Dietary intervention comprises dietary education and follow-up provided by a dietitian. The first dietary counselling session is 1 hour and follow up sessions comprise 30 minutes. There are monthly consultations for the first 3 months, followed by 3-monthly consultations (ie at 6,9, and 12 months of follow-up).
Sponsors
University of Wollongong
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
Overweight or obese Body Mass Index (BMI) >25 and =< 37 kg/m2
Exclusion criteria
Major illnesses, diabetes mellitus, Low density lipoprotein (LDL) > 6 mmol/l, food allergies or habits inhibiting compliance, illiteracy and inadequate conversational English, inability to undertake study requirements, taking fish oil supplements, pregnancy/lactation, not weight stable for past six months (within 3kg), or on a weight-reducing diet
Outcome results
None listed