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Randomised controlled trial of routine replacement of peripheral cannulae versus removal on clinical indication

Randomised controlled trial of routine replacement of peripheral cannulae versus removal on clinical indication for the prevention of phlebitis

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12608000421336
Enrollment
754
Registered
2008-08-25
Start date
2008-05-20
Completion date
2009-09-09
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

In Australia each year ten million intravenous (IV) drips are inserted in patients’ arms or in the backs of their hands to give fluid and medications. Many drips are routinely replaced every few days in the hope that this reduces infection, however preliminary research suggests it would be better and more cost effective to leave them alone. That would save patients the pain of another needle as well as interruption to treatment. It would save doctors and nurses time, and reduce waste from plastic disposables. The research will provide the evidence to know one way or the other whether IV drips should be routinely changed or left alone.

Interventions

Generic hospital patients from medical/surgical/oncology wards with a peripheral intravenous device (IV) will have this used for 72-96 hours. The IV will then be removed and a new IV will be inserted into a different vein. This will continue for the course of treatment (e.g. the course of antibiotics or rehydration).

Sponsors

Griffith University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Peripheral cannulae in situ as part of routine clinical care for 3 days, written consent

Exclusion criteria

Current bloodstream infection, immunosuppressed, planned intravenous device (IV) removal within 24 hours

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 30, 2026