Effect of a 3 second inspiratory time on pattern of ventilation and sputum cleared during manual hyperinflation

Effect of a 3 second inspiratory time during manual hyperinflation compared to current practice, on pattern of ventilation and sputum cleared in patients intubated for at least 2 days.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000418370

Enrollment

Registered

2008-08-25

Start date

2003-08-27

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Manual hyperinflation is a physiotherapy treatment technique where patients with a breathing tube for artificial (mechanical) ventilation are given a deep breath by squeezing a small bag with an air/oxygen mix. The aim of this study is to investigate whether how physiotherapists perform this technique affects the amount of mucus (phlegm) cleared from the lungs.

Interventions

manual hyperinflation with a 3 second inspiratory time peak inspiratory pressure limited to 40 cmH2O 6 sets of 6 breaths, once daily over 2 days therapist trained specifically to perfom manual hyperinflation with 3 second inspiratory time minimum of 2 hour wash-out period between interventions

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

intubated for at least 2 days and likely to remain so for the next 2 days

Exclusion criteria

inability of the person approached for consent to understand English, head injury with intracranial pressure >/= 15 cmH2O or being managed by hyperventilation, systolic blood pressure (BP) <100 or > 180 mmHg, mean arterial blood pressure <70 or > 110 mmHg, heart rate <70 or >120 bpm, on inotropic support, pneumothorax without an intercostal catheter in situ, subcutaneous emphysema or intercostal catheter with an air leak, requiring positive expiratory pressure (PEEP) >/= 10 cmH2O during synchronised intermittent mandatory ventilation (SIMV), on continous positive airway pressure (CPAP) >/= 15 cmH2O and oxygen >50%, adult respiratory distress syndrome, acute pulmonary oedema, acute bronchospasm, baseline peak inspiratory pressure > 40 cmH2O

Outcome results