None listed
Conditions
Brief summary
The aim was to study whether indigo carmine dye spray colonoscopy increases a detection rate of colorectal polyp including flat adenoma in an Australian population.
Interventions
During colonoscopy, 0.2% indigo carmine solution was applied down the side-channel of the instrument using a 20mL syringe containing 5mL indigo carmine and a cushion of air. A minimum volume of 20ml of indigo carmine was applied diffusely to the entire right colon (defined as proximal to the splenic flexure), and in a targeted fashion to the left colon, on any suspicious areas of the colonic mucosa. Recruitment ceased when 200 patients had been recruited into each arm.
Sponsors
Mark N Appleyard
Study design
Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
19 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
Consecutive unselected patients presenting for colonoscopy. Colonoscopy was performed for standard clinical indications.
Exclusion criteria
Known polyposis syndromes, hereditary non-polyposis colorectal cancer, inflammatory bowel disease and patients referred for polypectomy from other institutions. Additional exclusion criteria included: poor bowel preparation, incomplete colonoscopy, anticoagulant therapy and patient refusal.
Outcome results
None listed