None listed
Conditions
Brief summary
The trial completed recruitment and data collection in 2011. Results presented at the European Cystic Fibrosis Conference and the Australasian Cystic Fibrosis Conference in 2011. Manuscript under preparation.
Interventions
Treadmill exercise, speed and incline set to achieve an exercise intensity of 60% of each subject's peak VO2 for 20 minutes on one occasion. Peak VO2 measured on the day prior to randomisation.
Positive expiratory pressure (PEP). Subjects breath through a PEP device which provides an expiratory pressure at the mouth of 15-20cmH2O. Subjects breath through this device for 15 breaths, followed by the Forced Expiratory Techinique. This cycle is repeated six times in a 20 minute period on one occasio
Treadmill exercise, speed and incline set to achieve an exercise intensity of 60% of each subject's peak VO2 for 20 minutes on one occasion. Peak VO2 measured on the day prior to randomisation. Positive expiratory pressure (PEP). Subjects breath through a PEP device which provides an expiratory pressure at the mouth of 15-20cmH2O. Subjects breath through this device for 15 breaths, followed by the Forced Expiratory Techinique. This cycle is repeated six times in a 20 minute period on one occasion. Control (resting breathing). Sitting quietly, relaxed breathing for 20 minutes on one occasion.
Sponsors
Royal Prince Alfred Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
diagnosed with cystic fibrosis, stable clinical condition
Exclusion criteria
previous lung transplant, pregnant, if participation resulted in the 5 year radiation does for volunteers being exceeded
Outcome results
None listed