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Long term outcome after endoscopic treatment of necrosis due to pancreatitis.

Transluminal Endoscopic Necrosectomy after Acute Pancreatitis: a Multicenter Study with Long-Term Follow-up (the GEPARD Study). Evaluation of peri- and post-procedural mortality and morbidity as well as long-term follow-up evaluation of survival, indication to surgery and quality of life.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12608000257369
Acronym
GEPARD
Enrollment
120
Registered
2008-05-20
Start date
1999-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

infected necrosis after acute necrotizing pancreatitis was treated with a transluminal endoscopic approach. the long term clinical outcome was evaluated retrospectively over a follow-up of 2 to 8 years.

Interventions

Transluminal endoscopic necrosectomy: 1)transgastric or transduodenal access to the retroperitoneal cavity using endoscopic or endosonographic guidance. 2)balloon dilation of the access was carried out to permit the introduction of a conventional gastroscope to allow forceful irrigation and suction, as well as active endoscopic removal of debris using snares, forceps, and stone removal baskets. 3)Repeated sessions at intervals of 1–4 days were carried out until all debris and necrotic material h

Transluminal endoscopic necrosectomy: 1)transgastric or transduodenal access to the retroperitoneal cavity using endoscopic or endosonographic guidance. 2)balloon dilation of the access was carried out to permit the introduction of a conventional gastroscope to allow forceful irrigation and suction, as well as active endoscopic removal of debris using snares, forceps, and stone removal baskets. 3)Repeated sessions at intervals of 1–4 days were carried out until all debris and necrotic material had been removed and the walls of the collections could be seen as vital structures. The duration of a session was determined mainly by patient tolerance of sedation or general anesthesia, but was usually limited to 90 minutes.

Sponsors

Charite - Medizinische Klinik m.S. Gastroenterologie
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

infected peripancreatic / retroperitoneal necrosis

Exclusion criteria

Gastric varices

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026