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Effect of exercise therapy on lipid profile and oxidative stress indicators in patients with type 2 diabetes

Effect of exercise therapy on lipid profile and oxidative stress indicators in patients with type 2 diabetes

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12608000217303
Enrollment
231
Registered
2008-04-21
Start date
1998-09-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Diabetes mellitus is a worldwide health problem predisposing to markedly increased cardiovascular mortality and morbidity. Lipid abnormalities significantly contribute to the increased risk of cardiovascular disease and other morbidity in diabetics. This study investigated the impact of Hatha yoga and conventional physical training exercise regimens on biochemical, oxidative stress indicators and oxidant status in patients with type 2 diabetes mellitus. The study hypothesis is that Hatha yoga exercise as well as conventional physical training exercise has therapeutic preventative and protective effects on diabetes mellitus by decreasing blood glucose and oxidative stress, and improving antioxidant status.

Interventions

Intervention for Group 1: Each yoga session consisted of 20 minutes of pranayamas (breath-control exercises), 25 minutes of dynamic warm-up exercises, 60 minutes of asanas (yogic postures), and 15 minutes of supine relaxation in savasana (corpse pose). A single session last for 2 hours. The Hatha yoga exercise sessions were conducted once per week for six months. Daily home exercise 3 – 4 times per week for 1 hour in the same Rate of Perceived Exertion was encouraged. Intervention for Group 2

Intervention for Group 1: Each yoga session consisted of 20 minutes of pranayamas (breath-control exercises), 25 minutes of dynamic warm-up exercises, 60 minutes of asanas (yogic postures), and 15 minutes of supine relaxation in savasana (corpse pose). A single session last for 2 hours. The Hatha yoga exercise sessions were conducted once per week for six months. Daily home exercise 3 – 4 times per week for 1 hour in the same Rate of Perceived Exertion was encouraged. Intervention for Group 2: The conventional physical training sessions consisted of 15 minutes of warm up exercises, 30 minutes of aerobic walking on an outdoor 400-meter track, 20 minutes of body flexibility exercises, 20 minutes of aerobic dance, 25 minutes of games and 10 minutes of warm down exercises. A single session last for 2 hours. The physical training exercise sessions were conducted once per week for six months. Daily home exercise 3 – 4 times per week for 1 hour in the same Rate of Perceived Exertion was encouraged. The duration of the study was for six months.

Sponsors

University of the West Indies
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

Type 2 diabetes mellitus subjects without malnutrition or severe complications of the disease (cardiovascular, renal, visual and cerebral), male or female, duration of the disease between 1-10 years, good psychological condition, non-smoker and non-alcoholic. Patient given written consent after provided with sufficient information about participation in the trial.

Exclusion criteria

Pregnant, high blood pressure, psychiatric disorders, severe heart failure or other acutely life-threatened conditions, severe chronic inflammatory disease, less than 40 years old, renal disease, duration of type 2 diabetes greater than 10 years, newly diagnosed persons with type diabetes.

Outcome results

None listed

Source: ANZCTR · Data processed: Apr 5, 2026