Determining peak inspiratory flow during regular breathing in both healthy and lung sick patients

A study to measure the peak flow of infants aged 0-2 years with either healthy lungs or with bronchiolitis to determine peak flow values in both these groups.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12608000215325

Enrollment

Registered

2008-04-21

Start date

2008-05-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Respiratory conditions are a common cause for hospital admission in the paediatric population, however little is known about paediatric respiratory function during regular breathing in these patients. The aim of this study is to determine the peak inspiratory flow rates, of both healthy and lung sick infants. It is hoped that this study will increase understanding of paediatric respiratory physiology during respiratory illness. The study will be a prospective, observational, unblinded study on infants with both normal and impaired respiratory function. The primary outcome will be Peak inspiratory flow – the maximum flow rate (LPM) recorded throughout the inspiration phase, during regular breathing. Once consent has been granted, the researcher will attach the flow sensor either via a face mask or if the infant is intubated via the endotrachela tube. Participants will be infants between 0 month and 2 years, recruited from Starship Childrens hospital, after obtained informed consent from parents/caregivers. It is approximated that 30 patients will be required in both groups.

Interventions

Peak flow will be measured in infants aged 0-2 years suffering from bronchiolitis. Peak flow will be measured using an ultrasonic flow meter for a time period of one minute. The flow sensor will be attached either via a face mask or if the infant is intubated via the endotracheal tube.

Eligibility

Sex/Gender

All

Age

0 to 2 Years

Healthy volunteers

Inclusion criteria

1. Infants aged 0-2 years 2. Infants about to undergo surgery not related to their respiratory system (healthy lung group) 3. Infants diagnosed with bronchiolitis in repsiratory failure (lung sick group)

Exclusion criteria

1. Infants aged > 2 years 2. Infants not breathing spontaneously 3. Infants whose condition limits their ability to participate 4. Infants where informed consent cannot be obtained from a parent or legal guardian

Outcome results