None listed
Conditions
Brief summary
The intervention trial is completed and is being analysed. The primary purpose of the study was to compare the effect of drinking red wine or de-alcoholised red wine on blood pressure and fatty acid metabolites involved in blood pressure regulation. This study specifically tests the effect of the alcohol in red wine compared with the polyphenols in red wine.
Interventions
Men who drink 40g of alcohol/day will be invited to participate in a 12 week trial of randomized block design, during which they will substitute the alcohol they drink for either 375 mol of water, or the equvalent volume of de-alcoholised red wine or red wine each for 4 weeks in crossover design without washout periods.
Sponsors
University of Western Austrlaia
Study design
Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
20 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
alcohol consumption >30g/day<110g/day, non-smokers, not taking medication
Exclusion criteria
smoking, alcohol consumption <30g/day or >110g/day. Taking medication
Outcome results
None listed