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Detection of recombinant human luteinising hormone (rLH) as a doping agent

Detection of recombinant human luteinising hormone as a doping agent in healthy male volunteers aged 18 to 45. An open label, randomised clinical study.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12608000181303
Enrollment
64
Registered
2008-04-10
Start date
2004-11-23
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Sports anti-doping study

Interventions

Half of the participants will have a 200mg injection of Nandrolone decanoate, then 3 days later a single dose of rLH 75IU or 225IU or recombinant human chorionic gonadotropin 'rhCG' 250ug or 750ug . Those given 'rhCG' will have another 100mg dose of Nandrolone decanoate the following day. The other half of the participants will be given either a single dose of either rLH 75IU or 225IU or rhCG 250ug or 750ug without the Nandrolone. Blood and urine samples will be obtained at intervals form 0 fo

Half of the participants will have a 200mg injection of Nandrolone decanoate, then 3 days later a single dose of rLH 75IU or 225IU or recombinant human chorionic gonadotropin 'rhCG' 250ug or 750ug . Those given 'rhCG' will have another 100mg dose of Nandrolone decanoate the following day. The other half of the participants will be given either a single dose of either rLH 75IU or 225IU or rhCG 250ug or 750ug without the Nandrolone. Blood and urine samples will be obtained at intervals form 0 for up to 8 days.

Sponsors

Sydney South Western Area Health Service (SSWAHS)
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

Healthy males

Exclusion criteria

No recent history of steriod use

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026