None listed
Conditions
Brief summary
This project will determine whether standard care or cardiology care improves survival for patients undergoing emergency orthopaedic-geriatric surgery with a troponin rise. A pilot study conducted at The Northern Hospital in 2006 revealed that at one year mortality rate was 21% in this population and those with a troponin rise were more at risk of dying. Therefore, this RCT is proposed to see if cardiology care is any better than standard care to improve survival.
Interventions
All recruited patients will have troponin blood tests and electrocardiographs (ECGs) done on post-operative days 1,2 and 3. Patients with a post-operative troponin rise will then be randomised to either standard care or cardiology care (the intervention). The cardiology care protocol involves a "total package" of care. This involves transfer to the coronary care unit for 24hours, review by a cardiologist and consideration for catheterisation if symptomatic. If not for catheterisation or if asymptomatic cardiology treatment will involve medical management with aspirin, beta blocker, statin +/- Angiotensin Converting Enzyme (ACE) inhibitor. All medications will be given orally with the dose and frequency at the discretion of the cardiologist. Duration of medication treatment will be for at least the duration of hospitalization with ongoing medication treatment at the discretion of the cardiologist. Patients randomised to coronary care will also have cardiac investigations including serial ECGs, chest x-ray, lipid profile, echocardiogram. All patients randomised to coronary care will also receive outpatient follow up by a cardiologist and a functional cardiac study (either dobutamine stress echocardiography or thallium stress test, only if they are a candidate for catheterisation in the future).
Sponsors
Study design
Eligibility
Inclusion criteria
Patients over 60 admited under the orthopaedic unit who undergo emergency surgery
Exclusion criteria
Elective surgery, die before surgery, admitted under a different unit, patients with an estimated mortality of less than 1 year (eg. terminal cancer), nursing home patients.